Peer Reviewed White Paper

Photodisinfection Therapy: Essential Technology for Infection Control

Jan. 17, 2020

Photodisinfection therapy (PDT) is a treatment modality that involves the administration of a light-sensitive compound, known as a photosensitizer (PS), followed by light irradiation at a specific wavelength that excites or “activates” the PS. PDT is minimally invasive and already used clinically to treat a wide range of medical conditions. In its antimicrobial form, (antimicrobial PDT – aPDT) it has been shown to eradicate pathogenic microorganisms such as Gram-positive and Gram-negative bacteria, viruses, protozoa, and fungi and, unlike traditional antibiotics, does not induce resistance following repeated exposures to the therapy (Pedigo et al, 2009; Tavares et al, 2010; Costa et al, 2011; Cabiscol et al, 2000; Lauro et al, 2002; Jori & Coppellotti, 2007; Cassidy et al, 2010; Giuliani et al, 2010; Martins et al, 2018; Al-Mutairi et al, 2018).

For these reasons, we believe aPDT will evolve into an essential tool for infection control and become a vital part of the solution to the global AMR crisis. This report will underscore explain the fundamental principles of aPDT and illustrate the ways in which aPDT can be used to reduce the risk of hospital-acquired infections and improve patient outcomes.

Click here to read the White Paper.